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Get the right START with SEROQUEL XR

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Get the right START with SEROQUEL XR

SEROQUEL XR is an extended‐release tablet, which means medicine is delivered around the clock. Because it is an extended-release medicine, the dose should be taken once a day, 3-4 hours before bedtime.

It is very important to follow your health care professional’s directions when you take SEROQUEL XR.

SEROQUEL XR is an extended‐release tablet, which means medication is delivered around the clock

TAKE SEROQUEL XR in the evening

ANTICIPATE possible drowsiness

REVIEW potential side effects here

TELL your health care provider how you’re feeling

It is important to talk to your doctor about how and when to take SEROQUEL XR in order to help manage your unresolved symptoms. It is also important to talk to your health care professional about all available options that may help you get closer to your treatment plan goals, including talk therapy.

Even if your symptoms go away and you are feeling better, you should continue taking SEROQUEL XR until your doctor tells you otherwise. Talk with your health care professional if you feel the need to stop treatment.

Conditions treated with SEROQUEL XR

How SEROQUEL XR can help

Extended‐release SEROQUEL XR is approved as add‐on treatment to antidepressants for major depressive disorder and to treat the depressive lows and manic highs of bipolar disorder.

  • SEROQUEL XR is an extended‐release tablet, which means medicine is delivered around the clock so you take it just once a day
  • SEROQUEL XR has been prescribed for more than 4 million people in the United States, across FDA‐approved uses

Taking SEROQUEL XR

SEROQUEL XR is an extended-release tablet you take by mouth. SEROQUEL XR tablets should be swallowed whole. The tablets should not be crushed, chewed, or split. Extended-release SEROQUEL XR should be taken as prescribed by your health care professional.

Take SEROQUEL XR only as your doctor prescribes. Your doctor may recommend that you take SEROQUEL XR once daily in the evening (for example, 3-4 hours before bedtime).

The XR in SEROQUEL XR stands for extended-release. This means the medicine is delivered around the clock.

If you miss a dose, take it as soon as you remember. If it is close to the next dose, skip the missed dose. Just take the next dose at your regular time. Do not take 2 doses at the same time unless your doctor tells you to. If you are not sure about your dosing, call your health care professional.

SEROQUEL XR should be taken without food or with a light meal (approximately 300 calories).

Everyone responds differently to therapy, so try to be patient and follow the directions of your health care professional. It is important to take SEROQUEL XR exactly as your health care professional has prescribed and to report your progress to your doctor.

Before taking SEROQUEL XR, tell your doctor if you have or have had any medical conditions such as:

  • Diabetes or high blood sugar in you or your family: your health care professional should check your blood sugar before you start SEROQUEL XR and also during therapy
  • High levels of total cholesterol, triglycerides, or LDL cholesterol or low levels of HDL cholesterol
  • Low or high blood pressure
  • Low white blood cell count
  • Cataracts
  • Seizures
  • Abnormal thyroid tests
  • High prolactin levels
  • Heart problems
  • Liver problems
  • Any other medical condition
  • Pregnancy or plans to become pregnant. It is not known if SEROQUEL XR will harm your unborn baby
  • Breast-feeding or plans to breast-feed. It is not known if SEROQUEL XR will pass into your breast milk. You and your health care professional should decide if you will take SEROQUEL XR or breast-feed. You should not do both

Tell your doctor about all the medicines that you take or recently have taken, including prescription medicines, nonprescription medicines, herbal supplements, and vitamins. SEROQUEL XR and other medicines may affect each other causing serious side effects. SEROQUEL XR may affect the way other medicines work, and other medicines may affect how SEROQUEL XR works.

Especially tell your health care professional if you take or plan to take medicines for:

  • Depression
  • High blood pressure
  • Parkinson's disease
  • Trouble sleeping

Tell your doctor if you take or plan to take any of these medicines:

  • Phenytoin, divalproex, or carbamazepine (for epilepsy)
  • Barbiturates (to help you sleep)
  • Rifampin (for tuberculosis)
  • Glucocorticoids (steroids for inflammation)
  • Thioridazine (an antipsychotic)
  • Ketoconazole, fluconazole, or itraconazole (for fungal infections)
  • Erythromycin (an antibiotic)
  • Protease inhibitors (for HIV)

This is not a complete list of medicines that can affect or be affected by SEROQUEL XR. Your doctor can tell you if it is safe to take SEROQUEL XR with your other medicines.

Do not start or stop any medicines while taking SEROQUEL XR without talking to your health care professional first. Know the medicines you take. Keep a list of your medicines to show your health care professional and pharmacist when you get a new medicine.

Tell your health care professional if you are having a urine drug screen because SEROQUEL XR may affect your test results. Tell those giving the test that you are taking SEROQUEL XR.

  • Do not drive, operate machinery, or do other dangerous activities until you know how SEROQUEL XR affects you. SEROQUEL XR may make you drowsy
  • Avoid getting overheated or dehydrated
  • Do not over-exercise
  • In hot weather, stay inside in a cool place if possible
  • Stay out of the sun. Do not wear too much clothing or heavy clothing
  • Drink plenty of water
  • Do not drink alcohol while taking SEROQUEL XR. It may make some side effects of SEROQUEL XR worse

Talk to your health care professional to find out whether SEROQUEL XR is right for you. SEROQUEL XR is covered on most commercial insurance plans. In addition, you could be eligible for monthly savings on out-of-pocket costs over $3.* Be sure to read the eligibility requirements.

*Up to a $185 savings limit per month.

What important information should I know about SEROQUEL XR?

Elderly patients with dementia‐related psychosis (having lost touch with reality due to confusion and memory loss) treated with this type of medicine are at an increased risk of death, compared to placebo (sugar pill). SEROQUEL XR is not approved for treating these patients.

Antidepressants have increased the risk of suicidal thoughts and actions in some children, teenagers, and young adults. Patients of all ages starting treatment should be watched closely for worsening of depression, suicidal thoughts or actions, unusual changes in behavior, agitation, and irritability. Patients, families, and caregivers should pay close attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed. These symptoms should be reported immediately to the doctor. SEROQUEL XR is not approved for children under the age of 10 years.

SEROQUEL XR side effects

What are the possible side effects of SEROQUEL XR?

SEROQUEL XR can cause serious side effects, including:

  • Stroke that can lead to death can happen in elderly people with dementia who take medicines like SEROQUEL XR
  • Neuroleptic malignant syndrome (NMS)
  • High blood sugar (hyperglycemia)
  • High fat levels in your blood (increased cholesterol and triglycerides)
  • Increase in weight (weight gain)
  • Movements you cannot control in your face, tongue, or other body parts (tardive dyskinesia)
  • Decreased blood pressure (orthostatic hypotension)
  • Increases in blood pressure in children and teenagers
  • Low white blood cell count
  • Cataracts
  • Seizures
  • Abnormal thyroid tests
  • Increases in prolactin levels
  • Sleepiness, drowsiness, feeling tired, difficulty thinking and doing normal activity
  • Increased body temperature
  • Difficulty swallowing
  • Trouble sleeping or trouble staying asleep (insomnia), nausea, or vomiting if you suddenly stop taking SEROQUEL XR. These symptoms usually get better 1 week after you start having them

What are the most common side effects of SEROQUEL XR?

It's best to be prepared for the possible side effects you may experience while taking SEROQUEL XR. For SEROQUEL XR, the most common side effects in adults across all indications are:

  • Drowsiness
  • Dry mouth
  • Constipation
  • Dizziness
  • Increased appetite
  • Upset stomach
  • Weight gain
  • Fatigue
  • Disturbance in speech and language
  • Stuffy nose

This is not a complete list of side effects of SEROQUEL XR. Please see additional information within the full Prescribing Information. By finding a treatment that works for you, and taking it regularly, you may experience improvement in your symptoms. Be patient and follow the directions of your health care professional.